About mesalamine
Aminosalicylate anti-inflammatory
Used for
- Treats mild to moderate inflammation of the rectum in ulcerative colitis.
Usual adult dose
Usually one suppository rectally three times daily for several weeks; dose and duration vary by product and condition.
Common side effects
- Rectal discomfort or irritation
- Abdominal pain, nausea, or diarrhea
- Headache
- Rare kidney inflammation or blood disorders
Important warnings
- Seek medical assessment for severe rash, breathing difficulty, unusual bruising, or reduced urination.
- Kidney function and blood counts may need monitoring during treatment.
- Avoid if allergic to mesalazine, salicylates, or related ingredients.
- Do not use a damaged or discolored suppository.
Pregnancy
Use only when considered necessary by a clinician; available evidence is generally reassuring, but discuss risks and benefits.
Breastfeeding
Small amounts may enter breast milk; use with clinical guidance and monitor for infant diarrhea.
Interactions
- Azathioprine or mercaptopurine: increased risk of blood disorders.
- Warfarin: mesalazine may affect anticoagulant effect.
- Other medicines that can harm the kidneys: increased kidney-related risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.