About indomethacin
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relieves pain and inflammation in arthritis
- Treats acute gout attacks
- Relieves pain from some muscle and joint conditions
Usual adult dose
Usually 75–150 mg daily in divided doses or as modified-release treatment; dose depends on condition.
Usual dose in children
Specialist dosing by weight for juvenile arthritis; not for routine use in children.
Common side effects
- Indigestion, nausea, or stomach pain
- Diarrhoea or headache
- Dizziness or drowsiness
- Stomach ulcer or bleeding
Important warnings
- Can cause serious stomach bleeding or ulcers.
- May increase risks of heart attack, stroke, and fluid retention.
- Avoid with other NSAIDs unless directed by a clinician.
- Use caution with kidney, liver, or heart disease and in older adults.
Pregnancy
Avoid from 20 weeks unless specifically advised; do not use from 30 weeks because of fetal risks.
Breastfeeding
Small amounts may enter milk; use only if a clinician considers it appropriate.
Interactions
- Blood thinners and antiplatelet medicines increase bleeding risk.
- Other NSAIDs, including aspirin, increase side effects.
- Diuretics, ACE inhibitors, or ARBs may worsen kidney function.
- Lithium or methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.