About valganciclovir hydrochloride eq to valganciclovir
Antiviral; cytomegalovirus treatment
Used for
- Treats cytomegalovirus (CMV) retinitis in adults with AIDS.
- Helps prevent CMV disease after kidney, heart, or kidney-pancreas transplantation.
Usual adult dose
CMV retinitis: 900 mg twice daily for 21 days, then 900 mg once daily. Prevention after transplant: usually 900 mg once daily; duration depends on transplant.
Usual dose in children
For children at least 4 months old after kidney or heart transplantation: dose is based on body size and kidney function; specialist dosing is required.
Common side effects
- Low white blood cells, red blood cells, or platelets
- Diarrhea, nausea, vomiting, or abdominal pain
- Fever, headache, or weakness
- Kidney problems
Important warnings
- Can cause severe blood-cell suppression; blood tests are needed.
- Can harm fertility and may cause fetal harm; use contraception as directed.
- Dose must be adjusted for reduced kidney function.
- Avoid handling crushed or broken tablets; the medicine may be harmful if absorbed.
Pregnancy
May cause fetal harm. Pregnancy testing and effective contraception during treatment and for 30 days afterward are recommended for females; males should use condoms during treatment and for 90 days afterward.
Breastfeeding
Breastfeeding is not recommended during treatment because of potential serious effects on the infant.
Interactions
- Imipenem-cilastatin may increase seizure risk.
- Didanosine levels may rise.
- Other medicines that suppress bone marrow can increase blood-cell problems.
- Medicines affecting kidney function may increase toxicity.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.