About metoclopr amide hydrochlo
Dopamine-blocking antiemetic and prokinetic
Used for
- Treats nausea and vomiting, including after surgery or chemotherapy.
- Helps stomach emptying in diabetic gastroparesis.
- May be used to prevent nausea during some procedures.
Usual adult dose
Usually 10 mg by injection up to three times daily; use the lowest effective dose for the shortest time.
Usual dose in children
For selected uses, 0.1–0.15 mg/kg per dose up to three times daily; specialist-directed, with age and weight limits.
Common side effects
- Drowsiness, dizziness, restlessness, or diarrhea
- Involuntary movements or muscle spasms
- Raised prolactin levels
- Rarely, severe allergic reaction or abnormal heart rhythm
Important warnings
- Can cause potentially lasting movement disorders; risk rises with longer use and higher doses.
- Avoid use with gastrointestinal bleeding, blockage, or perforation.
- Dose reduction may be needed with kidney impairment; follow local duration limits.
- May cause drowsiness; avoid driving if affected.
Pregnancy
May be used when clinically needed; safety depends on the situation and local guidance.
Breastfeeding
Passes into breast milk; may affect the infant or milk supply. Consider alternatives with a clinician.
Interactions
- Antipsychotics may increase movement-related side effects.
- Levodopa and dopamine agonists can have reduced effects.
- Opioids and sedatives may increase drowsiness.
- Serotonergic medicines may increase risk of serotonin syndrome.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.