About doxylamine succinate + pyridoxine hydrochloride
Antihistamine and vitamin B6 combination
Used for
- Treats nausea and vomiting during pregnancy.
Usual adult dose
Usually start with two tablets at bedtime; may increase to one each morning, afternoon, and bedtime as directed.
Common side effects
- Sleepiness
- Dizziness
- Dry mouth
- Constipation
Important warnings
- Can cause marked drowsiness; avoid driving if affected.
- Avoid alcohol and other sedating medicines unless advised by a clinician.
- Do not take with monoamine oxidase inhibitors.
- Swallow delayed-release tablets whole.
Pregnancy
Used for nausea and vomiting in pregnancy; evidence has not shown increased risk of birth defects.
Breastfeeding
Doxylamine may cause infant sleepiness or irritability and may reduce milk supply; use requires clinical guidance.
Interactions
- Alcohol, opioids, sleep medicines, and other sedatives can increase drowsiness.
- Monoamine oxidase inhibitors can intensify anticholinergic effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.