About acetaminophen + diphenhydramine hcl + pseudoephedrine hcl
Pain reliever, antihistamine, decongestant
Used for
- Short-term relief of fever, aches, runny nose, sneezing, and nasal congestion from colds.
Usual adult dose
Usually one tablet every 4–6 hours as needed; follow the package directions and maximum daily dose.
Usual dose in children
Not established for this combination; use only if the product label specifies an age-appropriate dose.
Common side effects
- Drowsiness, dizziness, or blurred vision
- Dry mouth or constipation
- Nausea
- Nervousness, trouble sleeping, or increased heart rate
Important warnings
- Avoid other medicines containing paracetamol; excess can severely damage the liver.
- May cause drowsiness; avoid alcohol and driving if affected.
- Use caution with high blood pressure, heart disease, glaucoma, or difficulty urinating.
- Seek urgent help for overdose or severe allergic symptoms.
Pregnancy
Ask a healthcare professional before use; pseudoephedrine is generally avoided during the first trimester and may affect blood pressure.
Breastfeeding
Ask a healthcare professional before use; diphenhydramine may affect milk supply or cause infant drowsiness, and pseudoephedrine may reduce milk production.
Interactions
- MAO inhibitors, including use within the past 14 days, can cause dangerous blood-pressure effects.
- Other sedatives or alcohol can increase drowsiness.
- Other decongestants or stimulants can increase blood pressure or heart rate.
- Other paracetamol-containing medicines increase liver-injury risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.