About sildenafil
Phosphodiesterase-5 inhibitor
Used for
- Erectile dysfunction
- Pulmonary arterial hypertension (different dosing and formulations)
Usual adult dose
Erectile dysfunction: usually 50 mg about one hour before sex; adjust to 25–100 mg, maximum once daily.
Common side effects
- Headache
- Flushing
- Indigestion
- Nasal congestion or visual changes
Important warnings
- Never combine with nitrate medicines or riociguat; blood pressure may fall dangerously.
- Seek urgent care for an erection lasting over four hours or sudden vision or hearing loss.
- Use caution with heart disease, low blood pressure, or medicines affecting sildenafil breakdown.
Pregnancy
Not established for erectile dysfunction; pulmonary hypertension use requires specialist assessment.
Breastfeeding
Not established; use for pulmonary hypertension requires specialist assessment.
Interactions
- Nitrates and riociguat are contraindicated.
- Alpha-blockers and blood-pressure medicines may increase dizziness or fainting.
- Strong CYP3A4 inhibitors, including ritonavir, can raise sildenafil levels.
- Other erectile dysfunction medicines should not be combined.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.