About amlodipine besilate
Dihydropyridine calcium-channel blocker
Used for
- High blood pressure
- Angina (chest pain)
- Certain coronary artery disease
Usual adult dose
Usually 5 mg once daily; maximum 10 mg once daily.
Usual dose in children
Ages 6–17: usually 2.5–5 mg once daily for high blood pressure.
Common side effects
- Ankle swelling
- Headache
- Dizziness
- Flushing
Important warnings
- May cause dizziness, especially when starting treatment or increasing the dose.
- Rarely, worsening chest pain or a heart attack can occur after starting or increasing the dose.
- Use cautiously in severe liver disease or certain heart conditions.
Pregnancy
Use only when clinically needed; safety information is limited, and treatment should be reviewed by a healthcare professional.
Breastfeeding
Amlodipine enters breast milk in small amounts; a healthcare professional can assess suitability.
Interactions
- Other blood-pressure medicines may increase dizziness or low blood pressure.
- Clarithromycin and some antifungals can increase amlodipine levels.
- Simvastatin levels may rise; doses above 20 mg daily may require review.
- Grapefruit may increase amlodipine levels in some people.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.