About exemestane
Aromatase inhibitor
Used for
- Treats hormone-sensitive early breast cancer after tamoxifen
- Treats advanced breast cancer after other hormone therapy
Usual adult dose
25 mg by mouth once daily after a meal.
Common side effects
- Hot flashes and sweating
- Joint or muscle pain
- Tiredness and trouble sleeping
- Nausea or headache
Important warnings
- Can reduce bone density and increase fracture risk
- May cause dizziness or fatigue
- Can harm an unborn baby; avoid pregnancy during treatment
- Usually unsuitable before menopause
Pregnancy
Avoid during pregnancy; it may harm the fetus. Effective contraception is needed during treatment and for one month afterward.
Breastfeeding
Do not breastfeed during treatment or for one month after the final dose.
Interactions
- Estrogen-containing medicines may reduce its effect
- Rifampin can lower exemestane levels
- Carbamazepine and phenytoin can lower exemestane levels
- St John's wort may lower exemestane levels
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.