About ozanimod as hcl
Sphingosine-1-phosphate receptor modulator
Used for
- Relapsing forms of multiple sclerosis in adults
- Moderate-to-severe ulcerative colitis in adults
Usual adult dose
Multiple sclerosis: Start with a 7-day dose increase, then once daily. Ulcerative colitis: Start with a 7-day dose increase, then once daily.
Common side effects
- Upper respiratory infections
- Headache
- Raised liver enzymes
- High blood pressure
Important warnings
- Can slow the heart rate, especially when starting treatment
- May increase infections; check vaccination status and avoid live vaccines during treatment
- Can cause macular swelling and liver injury
- Stopping treatment may rarely cause severe worsening of multiple sclerosis
Pregnancy
May harm an unborn baby. Effective contraception is recommended during treatment and for three months after stopping.
Breastfeeding
It is not known whether ozanimod passes into breast milk; discuss risks with a healthcare professional.
Interactions
- Avoid monoamine oxidase inhibitors
- Avoid live vaccines during treatment and for three months after stopping
- Other medicines that slow heart rate may increase cardiac effects
- Some medicines can raise ozanimod levels or increase infection risk
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.