About ampicillin
Penicillin antibiotic
Used for
- Treats susceptible bacterial infections, including respiratory, urinary, gastrointestinal, and skin infections
- Used for serious infections such as meningitis or bloodstream infections when appropriate
Usual adult dose
Usually 1–2 g intravenously every 4–6 hours; dose depends on infection and kidney function.
Usual dose in children
Usually 50–200 mg/kg/day intravenously, divided every 4–6 hours; specialist regimens vary by infection.
Common side effects
- Nausea, vomiting, or diarrhea
- Rash or allergic reaction
- Injection-site pain or inflammation
- Rarely, severe antibiotic-associated diarrhea
Important warnings
- Do not use with a serious penicillin allergy; cross-reactions with other beta-lactams can occur.
- Use only for bacterial infections; unnecessary use promotes antibiotic resistance.
- Dose adjustment may be needed with kidney impairment.
- Seek urgent care for breathing difficulty, facial swelling, or severe rash.
Pregnancy
Generally considered acceptable when needed; the prescriber should weigh benefits and risks.
Breastfeeding
Usually compatible; monitor the infant for diarrhea, rash, or thrush.
Interactions
- Probenecid can increase ampicillin levels.
- Allopurinol may increase the chance of rash.
- Ampicillin may reduce the effectiveness of oral typhoid vaccine.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.