About glibenclam ide
Sulfonylurea diabetes medicine
Used for
- Type 2 diabetes when diet and exercise alone are insufficient.
Usual adult dose
Usually 2.5–5 mg once daily with breakfast or the first main meal; adjusted according to blood glucose.
Common side effects
- Low blood sugar, sometimes severe
- Weight gain
- Nausea or stomach discomfort
- Skin rash or sensitivity to sunlight
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Low blood sugar risk increases with missed meals, alcohol, or strenuous exercise.
- Use cautiously with liver or kidney problems; severe impairment may make treatment unsuitable.
- Check glucose regularly, especially when starting or changing dose.
Pregnancy
Generally avoided; insulin is usually preferred. Use during pregnancy requires specialist supervision.
Breastfeeding
Usually avoided because of potential infant low blood sugar; alternatives are generally preferred.
Interactions
- Insulin and other diabetes medicines can increase low blood sugar risk.
- Some antibiotics, antifungals, and anti-inflammatory medicines may intensify its effect.
- Corticosteroids and some diuretics may raise blood glucose.
- Alcohol can cause reactions and unpredictable blood sugar changes.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.