About phenprocoumon
Vitamin K antagonist anticoagulant
Used for
- Prevents and treats blood clots, including deep vein thrombosis and pulmonary embolism.
- Prevents stroke and other clots in people with atrial fibrillation or certain artificial heart valves.
Usual adult dose
Individualized by blood tests (INR); dosing varies and must be adjusted regularly.
Common side effects
- Bleeding, including bruising, nosebleeds, or blood in urine or stool.
- Nausea, vomiting, or diarrhea.
- Rarely, painful skin damage or tissue death.
Important warnings
- Can cause serious or fatal bleeding; seek urgent care for severe bleeding or head injury.
- Regular INR blood tests are essential; dose changes require clinical supervision.
- Avoid during pregnancy, especially early and late pregnancy; it can harm the fetus.
- Tell healthcare professionals before surgery or dental procedures; do not stop without direction.
Pregnancy
Generally contraindicated because it can cause fetal harm, pregnancy loss, and bleeding complications.
Breastfeeding
Usually considered compatible with breastfeeding; confirm suitability with a healthcare professional.
Interactions
- Many medicines affect INR, including antibiotics, antifungals, pain relievers, and herbal products.
- Vitamin K intake changes can alter anticoagulant effect; keep dietary intake consistent.
- Alcohol may affect bleeding risk or INR.
- Other blood thinners and antiplatelet medicines increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.