About pantoprazole sodium sesquihydrate eq to pantoprazole
Proton pump inhibitor
Used for
- Gastro-oesophageal reflux and erosive oesophagitis
- Stomach or duodenal ulcers
- Prevention of ulcers from certain anti-inflammatory medicines
- Excess stomach acid, including Zollinger–Ellison syndrome
Usual adult dose
Usually 40 mg once daily; some conditions require twice-daily dosing or longer treatment.
Usual dose in children
For ages 5 years and older with reflux oesophagitis: usually 20 mg daily if under 40 kg, or 40 mg daily if 40 kg or more.
Common side effects
- Headache
- Diarrhoea
- Nausea or abdominal pain
- Long-term use may lower magnesium or vitamin B12
Important warnings
- Seek assessment for difficulty swallowing, unexplained weight loss, vomiting blood, or black stools.
- Long-term use may increase fracture risk and rarely cause kidney inflammation.
- May mask symptoms of stomach cancer; persistent symptoms need medical assessment.
- Do not stop prolonged treatment suddenly without medical guidance.
Pregnancy
Use only when needed after discussing benefits and risks with a healthcare professional.
Breastfeeding
Small amounts may enter breast milk; use only when needed after professional advice.
Interactions
- May reduce absorption of medicines needing stomach acid, such as some antifungals.
- Can affect warfarin; monitoring may be needed.
- May interact with high-dose methotrexate.
- Atazanavir and similar HIV medicines may work less well.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.