About BUPRENORP HINE 5 MCG/HR
Opioid partial agonist analgesic
Used for
- Long-term, severe pain requiring continuous opioid treatment when other options are inadequate.
Usual adult dose
Apply one patch every 7 days; prescribers may adjust gradually based on response.
Common side effects
- Nausea, constipation, dizziness, sleepiness
- Headache, vomiting, application-site reactions
- Breathing suppression, especially after starting or increasing treatment
Important warnings
- Can cause addiction, overdose, and life-threatening slowed breathing.
- Alcohol and sedatives can increase severe sleepiness and breathing problems.
- Do not cut or heat the patch; heat can increase medicine absorption.
- Not for occasional pain or opioid withdrawal treatment.
Pregnancy
Long-term use during pregnancy can cause newborn opioid withdrawal; use may also cause breathing problems in the newborn.
Breastfeeding
Buprenorphine passes into breast milk and may cause infant sleepiness or breathing problems; monitor for these effects.
Interactions
- Benzodiazepines, alcohol, and other sedatives increase breathing and sedation risks.
- Strong CYP3A4 inhibitors or inducers can alter buprenorphine levels.
- Other opioids and medicines that depress breathing increase overdose risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.