About human normal immunoglobulin
Subcutaneous immunoglobulin replacement therapy
Used for
- Replacement treatment for primary immunodeficiency in adults and children
- Replacement treatment for secondary immunodeficiency in adults
Usual adult dose
Usually 0.2–0.5 g/kg weekly, adjusted to clinical response and immunoglobulin levels.
Usual dose in children
Usually 0.2–0.5 g/kg weekly for primary immunodeficiency, adjusted to response and immunoglobulin levels.
Common side effects
- Injection-site pain, swelling, redness, or itching
- Headache
- Nausea
- Fatigue
Important warnings
- Rare severe allergic reactions can occur, especially with IgA deficiency and anti-IgA antibodies.
- Rare blood clots, kidney problems, or red blood cell breakdown may occur.
- Seek urgent care for breathing difficulty, severe chest pain, one-sided weakness, or severe allergic symptoms.
Pregnancy
Use when clinically needed; pregnancy experience is limited. Discuss treatment with a healthcare professional.
Breastfeeding
Immunoglobulins naturally occur in breast milk; use may be considered when clinically needed.
Interactions
- May interfere with the response to live vaccines, including measles, mumps, rubella, and varicella.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.