About digoxin
Cardiac glycoside
Used for
- Heart failure symptoms in selected patients
- Control of heart rate in atrial fibrillation
Usual adult dose
Usually 0.125–0.25 mg once daily; dose depends on kidney function, age, and blood levels.
Usual dose in children
Individualized by age, weight, and kidney function; specialist-directed dosing is required.
Common side effects
- Nausea, vomiting, or loss of appetite
- Dizziness, confusion, or fatigue
- Vision changes, including blurred or yellow vision
- Slow or irregular heartbeat
Important warnings
- Too much can cause dangerous heart rhythm problems.
- Kidney impairment, older age, and low potassium increase toxicity risk.
- Blood levels and kidney function may need monitoring.
- Seek urgent care for fainting or a markedly irregular heartbeat.
Pregnancy
May be used when clinically needed; dosing and monitoring require clinician oversight.
Breastfeeding
Generally compatible with breastfeeding; small amounts enter breast milk.
Interactions
- Amiodarone, verapamil, and some antibiotics can raise digoxin levels.
- Diuretics that lower potassium can increase toxicity risk.
- Antacids and some supplements can reduce absorption; separate doses as directed.
- St. John’s wort can reduce digoxin levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.