About foscarnet
Antiviral; pyrophosphate analogue
Used for
- Treats cytomegalovirus retinitis, especially in people with AIDS.
- Treats aciclovir-resistant herpes simplex infections.
- Treats selected ganciclovir-resistant cytomegalovirus infections.
Usual adult dose
Given by intravenous infusion; dosing depends on infection, kidney function, and treatment phase. Typical induction: 60 mg/kg every 8 hours or 90 mg/kg every 12 hours.
Common side effects
- Kidney injury
- Low calcium, magnesium, potassium, or phosphate
- Nausea, vomiting, or diarrhoea
- Genital ulcers or irritation
Important warnings
- Requires kidney-function monitoring and dose adjustment.
- Electrolyte changes can cause seizures or abnormal heart rhythms.
- Infusion must be given slowly with adequate hydration.
- Use caution with medicines that affect kidneys or heart rhythm.
Pregnancy
May harm an unborn baby; use during pregnancy only when clearly needed.
Breastfeeding
Breastfeeding is generally not recommended during treatment.
Interactions
- Other kidney-damaging medicines, including aminoglycosides and amphotericin B, may increase kidney injury.
- Medicines that prolong the QT interval may increase abnormal heart-rhythm risk.
- Zidovudine may increase blood-related side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.