About Serzone 200mg Tablets
Serotonin antagonist and reuptake inhibitor antidepressant
Used for
- Major depressive disorder
Usual adult dose
Usually 100 mg twice daily initially; adjusted gradually, commonly 200–300 mg twice daily.
Common side effects
- Drowsiness or dizziness
- Nausea
- Dry mouth
- Blurred vision
Important warnings
- Rare, potentially fatal liver failure; treatment requires careful monitoring.
- Avoid with certain medicines that strongly inhibit CYP3A4.
- Can increase suicidal thoughts, especially early in treatment or after dose changes.
- Do not stop suddenly without medical guidance.
Pregnancy
Use during pregnancy only when benefits outweigh potential risks; discuss risks with a clinician.
Breastfeeding
Limited information is available; potential infant effects should be considered with a clinician.
Interactions
- Do not combine with MAO inhibitors; allow appropriate washout periods.
- Strong CYP3A4 inhibitors can greatly increase nefazodone levels.
- Nefazodone can dangerously increase levels of some medicines, including certain statins.
- Alcohol and sedating medicines may worsen drowsiness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.