About Theraprim Forte Tablets
Combination antibiotic
Used for
- Susceptible urinary tract infections
- Certain bacterial respiratory infections
- Certain bacterial intestinal infections
- Treatment and prevention of Pneumocystis pneumonia
Usual adult dose
Usually one tablet twice daily for susceptible bacterial infections. Pneumocystis pneumonia requires higher, weight-based doses.
Usual dose in children
From 2 months: trimethoprim 4 mg/kg plus sulfamethoxazole 20 mg/kg per dose, twice daily for susceptible bacterial infections; use suitable formulations.
Common side effects
- Nausea and vomiting
- Diarrhea
- Skin rash
- Increased blood potassium
Important warnings
- Avoid with sulfonamide or trimethoprim allergy.
- Rare severe skin reactions and blood disorders can occur.
- Kidney impairment may require dose reduction.
- Can cause hemolysis in G6PD deficiency.
Pregnancy
Generally avoided, particularly during early pregnancy and near delivery; may affect folate metabolism and increase newborn risks.
Breastfeeding
Generally compatible with healthy, full-term infants; avoided when infants are premature, jaundiced, ill, or have G6PD deficiency.
Interactions
- Warfarin: increased bleeding risk
- Methotrexate: increased blood toxicity
- Spironolactone, ACE inhibitors, or ARBs: increased potassium
- Phenytoin: increased levels and toxicity
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.