About amlodipine besylate
Dihydropyridine calcium channel blocker
Used for
- High blood pressure
- Angina (chest pain)
- Coronary artery disease
Usual adult dose
Usually 5 mg once daily; maximum 10 mg once daily.
Usual dose in children
For ages 6–17: usually 2.5–5 mg once daily; maximum 5 mg daily.
Common side effects
- Ankle swelling
- Headache
- Flushing
- Dizziness
Important warnings
- May cause low blood pressure or fainting.
- Use cautiously with severe aortic stenosis or liver disease.
- Do not stop without medical guidance; chest pain may worsen.
- Seek urgent care for severe allergic swelling or worsening chest pain.
Pregnancy
Safety is not fully established; use during pregnancy only when prescribed after weighing benefits and risks.
Breastfeeding
Amlodipine passes into breast milk in small amounts; discuss benefits and risks with a healthcare professional.
Interactions
- Clarithromycin and some antifungals may increase amlodipine levels.
- Rifampin may reduce its effect.
- Simvastatin exposure may increase; doses may need limiting.
- Other blood-pressure medicines can increase dizziness or low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.