About perindopri l arginine
ACE inhibitor and thiazide-like diuretic combination
Used for
Usual adult dose
Usually one tablet once daily, taken in the morning.
Common side effects
- Dizziness or headache
- Dry cough
- Low blood pressure
- Changes in kidney function or blood salts
Important warnings
- Can cause dangerously low blood pressure, especially with dehydration.
- May impair kidney function or raise potassium; monitoring is needed.
- Avoid in pregnancy; can harm the developing baby.
- Not suitable with certain medicines, including sacubitril/valsartan.
Pregnancy
Not recommended; ACE inhibitors can harm or cause death of the developing baby, especially later in pregnancy.
Breastfeeding
Generally not recommended, particularly for newborns or premature infants; alternatives may be preferred.
Interactions
- Lithium: may increase lithium levels and toxicity.
- Potassium supplements or potassium-sparing medicines: may raise blood potassium.
- NSAIDs, including ibuprofen: may worsen kidney function and reduce blood-pressure control.
- Other blood-pressure medicines or diuretics: may increase low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.