About ubrogepant free base trihydrate equivalent to ubrogepant
Calcitonin gene-related peptide receptor antagonist
Used for
- Treats migraine attacks, with or without aura, in adults.
Usual adult dose
Take 50 or 100 mg by mouth; if needed, repeat after at least 2 hours. Maximum 200 mg in 24 hours.
Common side effects
- Nausea
- Sleepiness
- Dry mouth
Important warnings
- Not for preventing migraines or treating cluster headaches.
- Avoid with strong CYP3A4 inhibitors or inducers.
- A second dose is not recommended with severe liver or kidney impairment.
- Seek urgent care for swelling or trouble breathing, which may signal an allergic reaction.
Pregnancy
Human pregnancy information is limited; discuss use with a healthcare professional.
Breastfeeding
Information is limited; discuss use with a healthcare professional.
Interactions
- Strong CYP3A4 inhibitors can greatly increase ubrogepant levels.
- Strong CYP3A4 inducers can reduce its effect.
- Verapamil and other moderate CYP3A4 inhibitors may require dose adjustment.
- Avoid another ubrogepant dose within 24 hours of certain interacting medicines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.