About fondaparinux sodium
Synthetic factor Xa inhibitor anticoagulant
Used for
- Prevention of blood clots after certain surgeries or during acute illness
- Treatment of deep vein thrombosis and pulmonary embolism
- Treatment of unstable angina or certain heart attacks
Usual adult dose
Prevention: 2.5 mg under the skin once daily. Treatment: weight-based under-the-skin dosing once daily, usually with another anticoagulant.
Common side effects
- Bleeding
- Anemia
- Bruising or injection-site reactions
- Low blood potassium
Important warnings
- Can cause serious or fatal bleeding; avoid with active major bleeding.
- Not for use when kidney function is severely reduced.
- Spinal or epidural procedures can cause dangerous spinal bleeding.
- Use caution with low body weight or medicines that increase bleeding.
Pregnancy
Use only when clearly needed; evidence is limited, and other anticoagulants are often preferred during pregnancy.
Breastfeeding
It is unknown whether fondaparinux enters human milk; discuss risks and alternatives with a clinician.
Interactions
- Other anticoagulants, antiplatelet medicines, and NSAIDs increase bleeding risk.
- Some medicines affecting clotting may increase bleeding; review all medicines with a clinician.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.