About sugammade
Selective muscle relaxant reversal agent
Used for
- Reverses rocuronium or vecuronium muscle relaxation after surgery
Usual adult dose
Intravenously: 2 mg/kg for moderate blockade, 4 mg/kg for deep blockade, or 16 mg/kg for immediate reversal after rocuronium.
Usual dose in children
Children aged 2 years and older: 2 mg/kg intravenously for moderate blockade; 4 mg/kg for deep blockade where approved.
Common side effects
- Nausea and vomiting
- Headache
- Injection site discomfort
- Cough
Important warnings
- Can cause severe allergic reactions
- Can cause marked slowing of heartbeat, rarely cardiac arrest
- Not recommended in severe kidney impairment
- Breathing monitoring is essential until muscle strength fully recovers
Pregnancy
Human pregnancy data are limited. Use during pregnancy requires assessment of potential benefits and risks.
Breastfeeding
Human breastfeeding data are limited. Transfer into milk and effects on breastfed infants are uncertain.
Interactions
- Hormonal contraceptives: additional nonhormonal contraception is needed for seven days
- Toremifene may delay reversal
- Intravenous fusidic acid may reduce reversal effectiveness
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.