About mycophenolate mofetil usp
Immunosuppressant; antimetabolite
Used for
- Prevents organ rejection after kidney, heart, or liver transplant
- Treats certain autoimmune conditions, such as lupus nephritis, off-label
Usual adult dose
Transplant: typically 1,000 mg twice daily for kidney; 1,500 mg twice daily for heart or liver.
Usual dose in children
Kidney transplant: typically 600 mg/m² twice daily, maximum 1,000 mg per dose; specialist dosing required.
Common side effects
- Diarrhea, nausea, vomiting, or stomach pain
- Low blood-cell counts and increased infection risk
- Higher risk of certain cancers, including skin cancer
Important warnings
- Can cause serious birth defects or miscarriage; pregnancy prevention and testing are required.
- Do not take with active serious infection without specialist guidance.
- Regular blood tests are needed; avoid live vaccines.
- Use sun protection and limit exposure to sunlight.
Pregnancy
Can cause miscarriage and severe birth defects. Avoid during pregnancy unless no suitable alternative; strict pregnancy prevention is required.
Breastfeeding
Breastfeeding is generally not recommended during treatment because of potential serious harm to the infant.
Interactions
- Antacids containing magnesium or aluminum can reduce absorption.
- Cholestyramine and some phosphate binders can lower mycophenolate levels.
- Acyclovir or ganciclovir may increase blood-cell problems.
- Live vaccines may be unsafe or less effective.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.