About everolimu s
mTOR kinase inhibitor
Used for
- Certain advanced kidney cancers, breast cancers, and neuroendocrine tumors
- Certain brain tumors associated with tuberous sclerosis complex
- Seizures associated with tuberous sclerosis complex
Usual adult dose
Usually once daily; dose varies by cancer type and may be adjusted for side effects or interacting medicines.
Usual dose in children
For tuberous sclerosis complex, usually once daily; dose is based on body size and condition.
Common side effects
- Mouth sores
- Infections
- Rash
- Diarrhea or nausea
Important warnings
- Can cause serious infections and reduced blood cell counts.
- May cause lung inflammation, kidney problems, or high blood sugar.
- Can impair wound healing; avoid live vaccines during treatment.
- Regular blood tests and monitoring are needed.
Pregnancy
May harm an unborn baby. Effective contraception is recommended during treatment and for 8 weeks after the last dose.
Breastfeeding
Breastfeeding is not recommended during treatment and for 2 weeks after the last dose.
Interactions
- Strong CYP3A4/P-glycoprotein inhibitors can raise drug levels.
- Strong CYP3A4/P-glycoprotein inducers can lower drug levels.
- Grapefruit may increase drug levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.