About diazepam
Benzodiazepine sedative and anticonvulsant
Used for
- Severe anxiety or agitation when rapid treatment is needed
- Muscle spasms
- Seizures, including status epilepticus
- Sedation before procedures
Usual adult dose
Usually 2–10 mg by slow intravenous injection, adjusted to the condition and response; some uses require repeat dosing.
Usual dose in children
For seizures, typically 0.2–0.3 mg/kg by slow intravenous injection; dosing depends on age and clinical setting.
Common side effects
- Drowsiness, dizziness, and confusion
- Slow or shallow breathing
- Low blood pressure
- Injection-site pain or vein irritation
Important warnings
- Can cause profound sedation, respiratory depression, coma, or death, especially with opioids or alcohol.
- Intravenous doses require monitoring and immediate access to breathing support.
- Repeated use can cause dependence; sudden stopping after prolonged use may cause withdrawal seizures.
- Use cautiously in older adults and people with breathing problems or liver disease.
Pregnancy
May harm the unborn baby, particularly with prolonged use or near delivery; use only when clearly necessary.
Breastfeeding
Passes into breast milk and may cause infant sleepiness or poor feeding; repeated use is generally avoided.
Interactions
- Opioids, alcohol, and other sedatives increase breathing and sedation risks.
- Some antifungals, antibiotics, and other medicines can increase diazepam effects.
- Rifampicin and some seizure medicines can reduce diazepam effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.