About lercanidipi ne hcl
Dihydropyridine calcium-channel blocker
Used for
- Treats high blood pressure.
Usual adult dose
Usually 10 mg once daily, at least 15 minutes before breakfast; may increase to 20 mg daily.
Common side effects
- Headache or dizziness
- Flushing
- Ankle swelling
- Palpitations
Important warnings
- Avoid grapefruit and grapefruit juice.
- Not for severe liver or kidney disease, heart failure, or certain heart conditions.
- Can cause dizziness, especially when standing.
- Do not use with ciclosporin or strong CYP3A4 inhibitors.
Pregnancy
Not recommended during pregnancy; safety is not established.
Breastfeeding
Not recommended during breastfeeding because safety is not established.
Interactions
- Grapefruit increases lercanidipine levels.
- Ciclosporin can raise levels; combination is contraindicated.
- Strong CYP3A4 inhibitors, such as ketoconazole, can raise levels.
- Rifampicin and some seizure medicines can reduce its effect.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.