About cabazitaxe l
Taxane chemotherapy medicine
Used for
- Treats advanced prostate cancer that has worsened after docetaxel chemotherapy, with prednisone.
Usual adult dose
20 mg/m² by intravenous infusion every three weeks with prednisone; some patients receive 25 mg/m².
Common side effects
- Low white blood cells and serious infections
- Anemia and low platelets
- Diarrhea, nausea, vomiting, and constipation
- Fatigue, hair loss, and nerve problems
Important warnings
- Can cause life-threatening infections and bone-marrow suppression.
- Preventive growth-factor treatment is often recommended; blood counts require monitoring.
- Severe allergic reactions can occur; premedication and monitoring are required.
- Do not use with severe liver impairment; pregnancy exposure can harm a fetus.
Pregnancy
Not used during pregnancy; may harm the fetus. Effective contraception is required during treatment and for three months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for two months after the final dose.
Interactions
- Strong CYP3A inhibitors, such as clarithromycin, may increase cabazitaxel levels.
- Strong CYP3A inducers, such as rifampin, may reduce cabazitaxel levels.
- Anticoagulants and medicines affecting blood cells may increase bleeding or infection risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.