About aflibercept
Vascular endothelial growth factor inhibitor
Used for
- Treats wet age-related macular degeneration, diabetic macular edema, and retinal vein occlusion
- Treats retinopathy of prematurity in infants
Usual adult dose
Eye injection: usually 2 mg every 4 weeks initially, then every 8 weeks; schedules vary by condition.
Usual dose in children
For retinopathy of prematurity: eye injection, usually 0.4 mg per eye; specialist-directed.
Common side effects
- Eye pain, redness, or irritation
- Floaters or blurred vision
- Increased eye pressure
- Rarely, retinal detachment, eye infection, or blood clots
Important warnings
- Administered by injection into the eye, not for irrigation
- Seek urgent assessment for sudden vision changes or severe eye pain
- May increase eye pressure or cause serious eye infection
- Use caution with recent stroke or heart attack
Pregnancy
Pregnancy safety is uncertain; treatment is generally avoided unless clearly needed.
Breastfeeding
Effects during breastfeeding are uncertain; discuss treatment timing with a clinician.
Interactions
- Few known medicine interactions; tell the eye specialist about all medicines and supplements
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.