About misoprostol
Prostaglandin E1 analogue
Used for
- Prevention of stomach ulcers caused by NSAID pain medicines
- Medical abortion, with other medicines
- Management of miscarriage or postpartum bleeding in specific protocols
Usual adult dose
Ulcer prevention: 200 micrograms four times daily with food. Other uses follow specific clinical protocols.
Common side effects
- Diarrhea
- Abdominal cramps
- Nausea
- Uterine contractions and bleeding
Important warnings
- Can cause miscarriage, premature birth, or birth defects during pregnancy.
- For ulcer prevention, avoid during pregnancy; use requires effective contraception.
- Medical abortion or miscarriage care requires appropriate clinical guidance.
- Rarely causes severe bleeding, uterine rupture, or serious allergic reactions.
Pregnancy
Can cause miscarriage, premature birth, birth defects, or uterine rupture. Use only when specifically indicated under clinical care.
Breastfeeding
Small amounts may enter breast milk; diarrhea is possible but usually mild. Follow guidance for the specific use.
Interactions
- Antacids containing magnesium may worsen diarrhea.
- Oxytocin and other medicines that stimulate uterine contractions may increase uterine activity.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.