About ziconotide
N-type calcium channel blocker
Used for
- Treats severe, persistent pain in adults when other treatments are inadequate or unsuitable.
Usual adult dose
Given by continuous infusion into spinal fluid; started at no more than 2.4 mcg/day and increased gradually. Maximum 19.2 mcg/day.
Common side effects
- Dizziness
- Nausea
- Confusion or memory problems
- Unsteady walking
Important warnings
- For specialist intrathecal use only; never inject into a vein.
- Can cause severe confusion, hallucinations, mood changes, or suicidal thoughts.
- Dose increases may cause serious neurological effects; changes must be gradual.
- Not suitable for people with a history of psychosis.
Pregnancy
Human pregnancy information is limited; use only when a clinician judges it necessary.
Breastfeeding
It is unknown whether ziconotide enters breast milk; clinical guidance is needed.
Interactions
- Other medicines affecting the nervous system may increase confusion or impaired alertness.
- Intrathecal baclofen, opioids, or local anesthetics may increase neurological side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.