About vitamin k
Vitamin K1 (phytonadione)
Used for
- Treats or prevents bleeding caused by vitamin K deficiency.
- Reverses effects of warfarin and similar anticoagulants in selected cases.
- Prevents bleeding in newborn babies.
Usual adult dose
Dose depends on the cause and blood-clotting results; commonly 1–10 mg by slow intravenous injection for warfarin reversal.
Usual dose in children
Newborn prevention: commonly 1 mg intramuscularly after birth. Treatment doses depend on age and cause.
Common side effects
- Injection-site pain or swelling
- Flushing or sweating
- Rare severe allergic reactions, especially with intravenous use
Important warnings
- Intravenous injection must be given slowly; serious reactions can occur.
- Not all anticoagulant-related bleeding is treated with vitamin K alone.
- Doses depend on clotting tests, indication, and route.
- Use the formulation and route specified for the patient.
Pregnancy
Use only when clinically needed; safety depends on the indication and dose.
Breastfeeding
Generally compatible; use depends on the indication and dose.
Interactions
- Warfarin and related anticoagulants: vitamin K reduces their effect.
- Some antibiotics can alter vitamin K effects.
- Orlistat and bile-acid binders may reduce vitamin K absorption.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.