About vinflunine
Vinca alkaloid chemotherapy medicine
Used for
- Advanced or metastatic urothelial cancer (bladder or urinary tract cancer), usually after prior treatment.
Usual adult dose
Usually 320 mg/m² by intravenous infusion over 20 minutes every three weeks; dose may be adjusted.
Common side effects
- Low blood-cell counts, especially neutropenia and anemia
- Constipation, nausea, vomiting, or abdominal pain
- Tiredness, reduced appetite, or hair loss
- Nerve symptoms, such as numbness or tingling
Important warnings
- Can cause serious infections or bleeding from low blood counts.
- Bowel obstruction or severe constipation can occur.
- Can affect heart rhythm; monitoring may be needed.
- Administer only by trained professionals into a vein; leakage can damage tissue.
Pregnancy
May harm an unborn baby. Avoid pregnancy during treatment and use effective contraception; follow specialist guidance on timing.
Breastfeeding
Breastfeeding is not recommended during treatment because of possible serious harm to the infant.
Interactions
- Other medicines that suppress bone marrow can increase blood-count problems.
- Strong CYP3A4 inhibitors or inducers may alter vinflunine levels.
- Avoid live vaccines during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.