About vilazodone
Serotonin partial agonist and reuptake inhibitor
Used for
- Major depressive disorder in adults
Usual adult dose
Usually 20–40 mg once daily with food; start at 10 mg daily and increase gradually.
Common side effects
- Diarrhea
- Nausea
- Vomiting
- Insomnia
Important warnings
- May increase suicidal thoughts in children and young adults, especially early in treatment.
- Do not stop suddenly; withdrawal symptoms may occur.
- Screen for bipolar disorder; mania or hypomania may emerge.
- Risk of serotonin syndrome, bleeding, and low blood sodium.
Pregnancy
Use only when benefits outweigh risks; late-pregnancy exposure may cause newborn complications.
Breastfeeding
Information is limited; vilazodone may enter breast milk, so infant effects are uncertain.
Interactions
- MAO inhibitors: dangerous serotonin syndrome risk; avoid combination and observe washout periods.
- Other serotonergic medicines increase serotonin syndrome risk.
- NSAIDs, aspirin, and anticoagulants may increase bleeding.
- Strong CYP3A4 inhibitors can raise vilazodone levels; dose adjustment may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.