About vericiguat
Soluble guanylate cyclase stimulator
Used for
- Reduces risk of cardiovascular death and heart-failure hospitalization in adults with symptomatic chronic heart failure and reduced ejection fraction, after a recent worsening event.
Usual adult dose
Start 2.5 mg once daily with food; double about every two weeks as tolerated to 10 mg once daily.
Common side effects
- Low blood pressure
- Anemia
- Dizziness
- Nausea
Important warnings
- Not for pregnancy; fetal harm is possible.
- Avoid with other soluble guanylate cyclase stimulators, such as riociguat.
- Do not use with PDE-5 inhibitors, such as sildenafil.
- Monitor blood pressure and anemia.
Pregnancy
May cause fetal harm. Pregnancy status is checked before treatment; effective contraception is advised during treatment and for one month afterward.
Breastfeeding
It is not known whether vericiguat passes into breast milk. Breastfeeding is not recommended during treatment.
Interactions
- PDE-5 inhibitors, including sildenafil and tadalafil, can cause low blood pressure.
- Other soluble guanylate cyclase stimulators, including riociguat, must not be combined.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.