About varicella zoster virus glycoprotein e
Recombinant shingles vaccine
Used for
- Prevents shingles (herpes zoster) and related nerve pain in adults aged 50 years and older.
- Prevents shingles in adults aged 18 years and older at increased risk due to immunodeficiency or immunosuppression.
Usual adult dose
Two doses of 0.5 mL, usually 2–6 months apart. For some immunocompromised adults, the second dose may be given 1–2 months after the first.
Common side effects
- Injection-site pain, redness, or swelling
- Muscle pain, fatigue, headache, or chills
- Fever or nausea
- Rare severe allergic reaction
Important warnings
- Not for preventing chickenpox or treating active shingles.
- Delay vaccination during a severe acute illness; mild illness is generally not a reason to delay.
- Do not give to anyone with a severe allergic reaction to a previous dose or vaccine component.
- Fainting can occur after vaccination; observation while seated may help prevent injury.
Pregnancy
There are no adequate pregnancy data. Routine vaccination is generally deferred until after pregnancy; discuss exposure or special circumstances with a clinician.
Breastfeeding
It is unknown whether vaccine components enter breast milk. A clinician can weigh vaccination benefits and uncertainties during breastfeeding.
Interactions
- Immunosuppressive treatments may reduce vaccine response; timing may affect protection.
- May be given with certain other vaccines at separate injection sites; side effects may increase.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.