About vancomyci n m
Glycopeptide antibiotic
Used for
- Serious infections caused by susceptible Gram-positive bacteria, including MRSA.
- Certain serious infections when other antibiotics are unsuitable.
Usual adult dose
Usually 15–20 mg/kg intravenously every 8–12 hours; dosing depends on kidney function and blood-level monitoring.
Usual dose in children
Children: usually 10–15 mg/kg intravenously every 6 hours; specialist dosing and monitoring are needed.
Common side effects
- Kidney injury
- Infusion reactions, including flushing and itching
- Low blood counts
- Hearing problems, rarely
Important warnings
- Must be given by slow intravenous infusion; rapid infusion can cause severe reactions.
- Kidney function and drug levels may require monitoring.
- Use cautiously with other medicines that can harm the kidneys or hearing.
- Not effective against viruses or most Gram-negative bacteria.
Pregnancy
May be used for serious infections when needed; available pregnancy data are limited.
Breastfeeding
Passes into breast milk, but infant absorption is expected to be low; monitor for diarrhea or thrush.
Interactions
- Aminoglycosides and other kidney- or hearing-damaging medicines may increase toxicity.
- Some anesthetics may increase infusion-related reactions.
- Other medicines affecting kidney function may require closer monitoring.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.