About valgancicl ovir
Antiviral; cytomegalovirus treatment
Used for
- Treats cytomegalovirus (CMV) retinitis in adults with AIDS.
- Prevents CMV disease after organ transplantation in selected adults and children.
Usual adult dose
CMV retinitis: 900 mg twice daily for 21 days, then 900 mg daily. Prevention: usually 900 mg daily; kidney function affects dosing.
Usual dose in children
For prevention after kidney or heart transplantation, dosing is based on age, height, weight, and kidney function.
Common side effects
- Low blood-cell counts, including anemia and neutropenia
- Diarrhea, nausea, vomiting, or abdominal pain
- Headache or fever
- Kidney problems
Important warnings
- Can cause severe bone-marrow suppression and infections or bleeding.
- May impair fertility and cause fetal harm; animal studies found cancer and birth defects.
- Dose must be adjusted for kidney function; blood counts require monitoring.
- Do not confuse valganciclovir tablets with ganciclovir capsules or oral solution.
Pregnancy
May cause fetal harm. Effective contraception is advised during treatment and for 30 days afterward for females, and 90 days for males.
Breastfeeding
Breastfeeding is not recommended during treatment because of potential serious effects in the infant.
Interactions
- Imipenem-cilastatin may increase seizure risk.
- Didanosine levels may rise.
- Mycophenolate may increase blood-cell toxicity.
- Other medicines that suppress bone marrow or harm kidneys may increase toxicity.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.