About vaccine tetanus antitoxin
Equine tetanus antibodies, not vaccine
Used for
- Temporary protection after tetanus-prone wounds in inadequately immunized people
- Treatment of tetanus alongside other hospital treatments
Usual adult dose
Prevention: one intramuscular dose according to local protocols. Treatment: higher, hospital-directed doses. Human tetanus immune globulin is preferred when available.
Usual dose in children
Prevention: one intramuscular dose according to local protocols. Treatment: hospital-directed dosing. Human tetanus immune globulin is preferred when available.
Common side effects
- Injection-site pain, redness, or swelling
- Fever
- Rash or hives
- Delayed serum sickness with fever, rash, and joint pain
Important warnings
- Can cause severe allergic reactions, including anaphylaxis
- Previous horse-serum exposure increases allergic reaction risk
- Does not replace tetanus vaccination or proper wound care
- Administration requires facilities equipped to manage severe allergic reactions
Pregnancy
Pregnancy data are limited; use when clinically indicated after weighing benefits and risks. Human tetanus immune globulin is preferred.
Breastfeeding
Breastfeeding data are limited; significant infant exposure is unlikely because antibodies are poorly absorbed orally.
Interactions
- Tetanus vaccine: administer separately at a different injection site
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.