About urapidil
Alpha-1 blocker and serotonin 5-HT1A agonist
Used for
- Severe high blood pressure requiring rapid treatment
- Blood pressure control during or after surgery
Usual adult dose
Given intravenously by healthcare professionals; commonly 10–50 mg slowly, then an infusion adjusted to blood pressure.
Common side effects
- Dizziness or headache
- Nausea
- Low blood pressure
- Slow or irregular heartbeat
Important warnings
- Can cause a sudden fall in blood pressure, especially if injected rapidly.
- Requires close blood-pressure and heart-rate monitoring.
- Use caution with severe liver or kidney problems.
- Not for use with certain heart conditions, including aortic stenosis.
Pregnancy
Use only when clearly needed; human pregnancy data are limited, and treatment requires specialist assessment.
Breastfeeding
Breastfeeding safety is not well established; a clinician should assess use.
Interactions
- Other blood-pressure-lowering medicines may increase low blood pressure.
- Cimetidine may increase urapidil levels.
- Alcohol may worsen blood-pressure-lowering effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.