About trientine tetrahydrochloride
Copper-chelating agent
Used for
- Treats Wilson disease by helping remove excess copper.
Usual adult dose
Usually 450–975 mg daily in divided doses; adjusted according to response and copper levels.
Usual dose in children
Usually 450–975 mg daily in divided doses; specialist-adjusted by age, weight, and response.
Common side effects
- Nausea or stomach discomfort
- Iron deficiency or anemia
- Rash or itching
- Joint pain
Important warnings
- Take on an empty stomach, separated from food and other medicines.
- Can cause iron deficiency; blood counts and iron status may need monitoring.
- Avoid taking with iron supplements unless specifically directed.
- Do not stop treatment abruptly; excess copper can build up.
Pregnancy
Use only when needed, with specialist monitoring; stopping treatment may harm the mother and fetus.
Breastfeeding
Human data are limited; discuss treatment with a specialist, as Wilson disease requires ongoing therapy.
Interactions
- Iron supplements reduce absorption; separate doses by at least two hours.
- Food, milk, and mineral supplements can reduce absorption.
- Antacids containing minerals may reduce absorption; separate doses.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.