About trientine hydrochloride
Copper-chelating agent
Used for
- Treats Wilson disease by removing excess copper from the body.
Usual adult dose
Usually 750–1,500 mg daily by mouth in divided doses; dose is individualized and adjusted by a specialist.
Usual dose in children
Usually 20 mg/kg daily by mouth in divided doses, up to 1,500 mg daily; specialist-adjusted.
Common side effects
- Iron-deficiency anemia
- Stomach upset or abdominal pain
- Skin rash or itching
- Joint pain
Important warnings
- Take on an empty stomach, separated from food and other medicines as directed.
- Can cause low iron; blood counts and iron levels need monitoring.
- Avoid taking with iron supplements unless specifically directed.
- Do not stop treatment abruptly; copper can build up again.
Pregnancy
Use only under specialist supervision; untreated Wilson disease also poses serious risks during pregnancy.
Breastfeeding
Information is limited; specialist guidance is needed to weigh treatment benefits and possible risks.
Interactions
- Iron supplements reduce absorption; separate doses by at least two hours.
- Antacids containing calcium, magnesium, or aluminum may reduce absorption; separate doses.
- Food and milk can reduce absorption; take apart from meals as directed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.