About trandolapril
ACE inhibitor blood pressure medicine
Used for
- High blood pressure
- Heart failure after a heart attack
Usual adult dose
High blood pressure: usually 1 mg once daily, adjusted gradually; maximum 4 mg daily. Heart failure after a heart attack: usually 1 mg daily, adjusted as tolerated.
Common side effects
- Dry cough
- Dizziness or low blood pressure
- High potassium
- Kidney function changes
Important warnings
- Can cause serious harm or death to an unborn baby; stop if pregnancy occurs.
- Avoid with prior ACE-inhibitor-related angioedema; facial or throat swelling needs emergency care.
- Risk of low blood pressure, kidney injury, and high potassium; monitoring may be needed.
- Do not combine with aliskiren in people with diabetes.
Pregnancy
Not safe during pregnancy, especially after the first trimester; can cause fetal injury or death.
Breastfeeding
Information is limited; use in newborns or premature infants is generally avoided. Discuss alternatives with a clinician.
Interactions
- Aliskiren or sacubitril/valsartan can increase serious adverse effects; required separation applies with sacubitril/valsartan.
- Potassium supplements, salt substitutes, or potassium-sparing diuretics can raise potassium.
- NSAIDs such as ibuprofen may impair kidney function and reduce blood-pressure effects.
- Lithium levels may rise, increasing toxicity risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.