About toremifene citrate
Selective estrogen receptor modulator
Used for
- Treats hormone-sensitive metastatic breast cancer in postmenopausal women.
- May be used for certain estrogen receptor-positive breast cancers.
Usual adult dose
60 mg by mouth once daily for metastatic breast cancer.
Common side effects
- Hot flashes and sweating
- Nausea
- Vaginal discharge
- Swelling or fluid retention
Important warnings
- Can prolong the heart’s QT interval, causing potentially serious abnormal rhythms.
- Avoid with congenital long-QT syndrome or certain medicines that prolong QT.
- May increase blood-clot risk.
- Liver problems can affect treatment safety.
Pregnancy
Not indicated during pregnancy; may harm a developing fetus. Pregnancy prevention is important during treatment.
Breastfeeding
Breastfeeding is not recommended during treatment.
Interactions
- QT-prolonging medicines can increase risk of abnormal heart rhythms.
- Strong CYP3A4 inhibitors may raise toremifene levels.
- Enzyme-inducing medicines, such as rifampin, may reduce its effectiveness.
- Warfarin effects may increase; monitoring is needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.