About tirofiban
Antiplatelet glycoprotein IIb/IIIa inhibitor
Used for
- Reduces blood clots in acute coronary syndrome
- Used with other treatments during certain coronary angioplasty procedures
Usual adult dose
Acute coronary syndrome: 0.4 micrograms/kg/minute for 30 minutes, then 0.1 micrograms/kg/minute by infusion. For angioplasty, dosing may differ.
Common side effects
- Bleeding
- Low platelet count
- Nausea
- Bruising
Important warnings
- Can cause serious or fatal bleeding
- Platelet counts require monitoring; treatment may need to stop if they fall
- Avoid or use cautiously with active bleeding or recent major surgery
- Dose adjustment may be needed with reduced kidney function
Pregnancy
Use only when clearly needed; human pregnancy information is limited, and bleeding risks must be considered.
Breastfeeding
It is not known whether tirofiban enters breast milk; breastfeeding decisions require clinical assessment.
Interactions
- Other blood thinners, including heparin, can increase bleeding
- Antiplatelet medicines, including aspirin or clopidogrel, can increase bleeding
- Nonsteroidal anti-inflammatory drugs can increase bleeding
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.