About teriflunomide
Pyrimidine synthesis inhibitor; immunomodulator
Used for
- Treats relapsing forms of multiple sclerosis in adults.
- May reduce relapses and slow worsening disability.
Usual adult dose
7 mg or 14 mg by mouth once daily.
Common side effects
- Diarrhea, nausea, or headache
- Hair thinning
- Increased liver enzymes
- Raised blood pressure
Important warnings
- Can cause serious liver injury; liver tests are needed.
- Can cause birth defects; pregnancy must be avoided during treatment.
- May lower blood cell counts and increase infection risk.
- Remains in the body for months; accelerated drug removal may be needed.
Pregnancy
Do not use during pregnancy. It may harm an unborn baby; effective contraception and drug elimination are important.
Breastfeeding
Breastfeeding is not recommended during treatment because of potential harm to the infant.
Interactions
- Other medicines that can damage the liver may increase liver-injury risk.
- May affect warfarin levels and require closer monitoring.
- Cholestyramine and activated charcoal can lower teriflunomide levels.
- Can interact with some medicines processed by liver enzymes or transporters.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.