About teprotumu mab
Insulin-like growth factor-1 receptor inhibitor
Used for
- Treats thyroid eye disease (Graves’ orbitopathy) in adults.
Usual adult dose
10 mg/kg by intravenous infusion once, then 20 mg/kg every three weeks for seven more infusions.
Common side effects
- Muscle spasms
- Nausea
- Hair loss
- Diarrhea
Important warnings
- Can cause hearing impairment, sometimes permanent.
- May worsen inflammatory bowel disease.
- Can cause high blood sugar; monitor glucose, especially with diabetes.
- May harm an unborn baby; pregnancy testing and effective contraception are recommended.
Pregnancy
May cause fetal harm. Avoid during pregnancy and use effective contraception during treatment and for six months after the last dose.
Breastfeeding
There are no adequate data on effects in breastfed infants or milk production; discuss risks with a healthcare professional.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.