About tenecteplase
Fibrinolytic (thrombolytic) medicine
Used for
- Breaks down blood clots in certain heart attacks.
- Treats acute ischaemic stroke in eligible patients, where approved.
- May be used for selected blood clots in other emergencies.
Usual adult dose
Given once by intravenous injection; dose depends on indication and body weight. For heart attack, weight-based dosing up to 50 mg.
Common side effects
- Bleeding, including serious internal or brain bleeding
- Nausea or vomiting
- Low blood pressure
- Allergic reactions
Important warnings
- Can cause life-threatening bleeding; use requires careful patient selection.
- Avoid or use cautiously with active bleeding, recent surgery, or bleeding disorders.
- Stroke treatment requires brain imaging and strict timing and eligibility criteria.
- Administer only in a monitored clinical setting.
Pregnancy
Limited information; bleeding risks and potential benefits require specialist assessment.
Breastfeeding
Not well studied; specialist assessment is needed, particularly after stroke treatment.
Interactions
- Anticoagulants and antiplatelet medicines increase bleeding risk.
- Other medicines that affect blood clotting may increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.